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मेटा-एनालिटिक प्रतिस्पर्धी जोखिम विश्लेषण×कॉक्स प्रोपोर्शनल हैज़र्ड्स×
क्षेत्रमहामारी विज्ञानमहामारी विज्ञान
परिवारProcess / pipelineProcess / pipeline
उद्भव वर्ष2000s–2010s (formalized as a pooled approach)1972
प्रवर्तकBased on Fine & Gray (1999) competing risks framework; meta-analytic synthesis methods established through methodological literature (mid-2000s onward)Sir David Roxbee Cox
प्रकारSystematic review / meta-analysisSemi-parametric regression model
मौलिक स्रोतRiley, R. D., Hayden, J. A., Steyerberg, E. W., et al. (2013). Prognosis Research Strategy (PROGRESS) 2: Prognostic Factor Research. PLOS Medicine, 10(2), e1001380. DOI ↗Cox, D. R. (1972). Regression models and life-tables. Journal of the Royal Statistical Society: Series B (Methodological), 34(2), 187–202. DOI ↗
उपनामmeta-analysis of competing risks, pooled competing risks analysis, systematic review competing risksCox regression, Cox PH model, proportional hazards model, CPH
संबंधित55
सारांशMeta-analytic competing risks analysis pools results from multiple primary studies that each used a competing risks framework, allowing summary estimates of cause-specific or subdistribution hazard ratios and cumulative incidence functions. Because standard meta-analytic methods may misrepresent competing events, specialized pooling strategies are required that respect the subdistribution hazard structure introduced by Fine and Gray and the distinction between cause-specific and all-cause hazard models.The Cox proportional hazards model is a semi-parametric regression method that estimates the effect of one or more covariates on the hazard — the instantaneous rate of an event such as death, relapse, or failure — while making no assumption about the shape of the baseline hazard function. Introduced by David Cox in 1972, it is the dominant tool for multivariable survival analysis in clinical and epidemiological research.
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