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सशर्त उत्तरजीविता और गतिशील पूर्वानुमान के लिए लैंडमार्क विश्लेषण×नेल्सन-एलेन संचयी संकट अनुमानक×
क्षेत्रउत्तरजीविताउत्तरजीविता
परिवारSurvival analysisSurvival analysis
उद्भव वर्ष19831972
प्रवर्तकAnderson, J. R., Cain, K. C. & Gelber, R. D.Wayne Nelson & Odd Aalen
प्रकारConditional survival estimatorNon-parametric cumulative hazard estimator
मौलिक स्रोतAnderson, J. R., Cain, K. C. & Gelber, R. D. (1983). Analysis of Survival by Tumor Response. Journal of Clinical Oncology, 1(11), 710–719. DOI ↗Nelson, W. (1972). Theory and applications of hazard plotting for censored failure data. Technometrics, 14(4), 945–966. DOI ↗
उपनामlandmark method, dynamic prediction, conditional survival estimation, Landmark Analizi (Dinamik Tahmin)Nelson-Aalen cumulative hazard, Aalen estimator, empirical cumulative hazard, Nelson-Aalen kümülatif hazard tahmincisi
संबंधित35
सारांशLandmark analysis, introduced by Anderson, Cain, and Gelber in 1983, estimates conditional survival probabilities for subjects who are still at risk at a pre-specified point in time — the landmark — rather than at study entry. It was developed explicitly to avoid immortal time bias that arises when subjects are grouped by an event (such as a treatment change or biomarker result) that can only occur if they remain event-free long enough to experience it.The Nelson-Aalen estimator is a non-parametric estimator of the cumulative hazard function from right-censored time-to-event data. Developed by Wayne Nelson for reliability hazard plotting in 1972 and placed on a rigorous counting-process foundation by Odd Aalen in 1978, it accumulates the ratio of observed events to the number at risk at each event time, providing the natural hazard-scale companion to the Kaplan-Meier survival curve.
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