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समतुल्यता / गैर-हीनता परीक्षण×टी-टेस्ट के लिए शक्ति विश्लेषण×
क्षेत्रप्रयोगात्मक अभिकल्पसांख्यिकी
परिवारHypothesis testHypothesis test
उद्भव वर्ष19871969
प्रवर्तकSchuirmann, D.J. / EMA regulatory frameworkJacob Cohen
प्रकारParametric equivalence / non-inferiority testSample size determination
मौलिक स्रोतSchuirmann, D.J. (1987). A Comparison of the Two One-Sided Tests Procedure and the Power Approach. Journal of Pharmacokinetics and Biopharmaceutics, 15(6), 657–680. link ↗Cohen, J. (1988). Statistical Power Analysis for the Behavioral Sciences (2nd ed.). Lawrence Erlbaum Associates. ISBN: 978-0805802832
उपनामnon-inferiority trial, bioequivalence study, active-control trial, Denklik ve Üstünlük Olmayan Çalışma (Equivalence / Non-Inferiority)t-test power analysis, sample size calculation for t-test, Güç Analizi — t-Testi
संबंधित65
सारांशAn equivalence or non-inferiority trial is a clinical study design that tests whether a new intervention is clinically equivalent to, or no worse than, an established standard by a pre-specified margin. Codified in Schuirmann's 1987 Two One-Sided Tests (TOST) framework and embedded in EMA and FDA regulatory guidance, this design is the regulatory standard for generic drug approval and medical device testing.Power analysis for the t-test is a sample size planning procedure that determines how many participants are required to detect a mean difference of a given magnitude with acceptable probability. Formalised by Jacob Cohen in his 1969 and 1988 editions of Statistical Power Analysis for the Behavioral Sciences, it links four quantities — effect size (Cohen's d), significance level (α), statistical power (1 − β), and sample size — so that fixing any three allows calculation of the fourth.
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