विधियों की तुलना करें

	Epigenome-wide association study in educational research	मेंडेलियन रैंडमाइजेशन (Mendelian Randomization)
क्षेत्र	जैव सूचना विज्ञान	कारणात्मक अनुमान
परिवार	Process / pipeline	Regression model
उद्भव वर्ष	EWAS framework ~2011; educational applications ~2017–present	1997
प्रवर्तक	Rakyan, Down, Balding, and Beck (framework); applied to educational outcomes by Marioni, McCartney, and collaborators	George Davey Smith
प्रकार	Observational epigenomic association design	Genetic instrumental variable framework
मौलिक स्रोत	Rakyan, V. K., Down, T. A., Balding, D. J., & Beck, S. (2011). Epigenome-wide association studies for common human diseases. Nature Reviews Genetics, 12(8), 529–541.	Davey Smith, G., & Hemani, G. (2014). Mendelian randomization: genetic anchors for causal inference in epidemiological studies. Human Molecular Genetics, 23(R1), R89-R98.
उपनाम	EWAS of educational attainment, educational EWAS, epigenetic association study, EWAS	MR
संबंधित	3	2
सारांश	An epigenome-wide association study (EWAS) applied to educational research scans DNA methylation levels at hundreds of thousands of CpG sites across the genome to identify loci whose methylation is statistically associated with educational attainment, cognitive ability, or related learning outcomes. By linking blood- or saliva-derived methylation profiles with school records or psychometric scores, EWAS offers a molecular window into how biological and environmental exposures may shape educationally relevant traits across the lifespan.	Mendelian randomization is a method for estimating causal effects of exposures on outcomes using genetic variants as instrumental variables. Introduced by George Davey Smith in the 1990s, it exploits Mendel's law of segregation to remove confounding bias. It has become a cornerstone technique in epidemiological causal inference.