השוואת שיטות

	סדרות עתיות מופרעות של אפקט טיפול הטרוגני (HTE-ITS)	ניתוח סדרות עתיות מופרעות (Interrupted Time Series - ITS)
תחום	הסקה סיבתית	הסקה סיבתית
משפחה	Regression model	Regression model
שנת המקור	2000s–2010s	2002
הוגה השיטה	Extensions of Shadish, Cook & Campbell (2002) ITS framework; HTE formulation developed by Lopez Bernal and colleagues	Wagner, Soumerai, Zhang & Ross-Degnan (segmented regression); Bernal, Cummins & Gasparrini (tutorial)
סוג	Quasi-experimental segmented regression with subgroup moderation	Quasi-experimental segmented regression
מקור מכונן	Lopez Bernal, J., Cummins, S., & Gasparrini, A. (2017). Interrupted time series regression for the evaluation of public health interventions: a tutorial. International Journal of Epidemiology, 46(1), 348-355.	Bernal, J. L., Cummins, S., & Gasparrini, A. (2017). Interrupted time series regression for the evaluation of public health interventions: a tutorial. International Journal of Epidemiology, 46(1), 348-355.
כינויים	HTE-ITS, Subgroup ITS, Effect-modifier ITS, Segmented ITS with interaction	ITS analysis, segmented regression of time series, Kesintili Zaman Serisi (ITS) Analizi
קשורות	4	5
תקציר	Heterogeneous Treatment Effect Interrupted Time Series extends the standard ITS design to detect whether an intervention's effect on a time series differs systematically across subgroups or in response to unit-level moderators. Where ordinary ITS yields a single level-change and slope-change estimate, HTE-ITS adds interaction terms for a moderating variable, revealing who benefits more or less from the intervention and by how much.	Interrupted Time Series analysis is a quasi-experimental design that estimates the effect of a single, well-dated intervention by comparing the trajectory of an outcome before and after it occurs. Formalised as segmented regression by Wagner and colleagues (2002) and popularised as a public-health evaluation tutorial by Bernal, Cummins and Gasparrini (2017), it separates the intervention's impact into a change in level and a change in slope.