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משפחהProcess / pipelineProcess / pipelineProcess / pipeline
שנת המקור1990s–2000s (Bayesian formalization)19581958
הוגה השיטהDeveloped from classical frequentist dose-response traditions; Bayesian formulations advanced by Dempster, Gelman, and colleaguesDavid Roxbee CoxEdward L. Kaplan and Paul Meier
סוגStatistical modeling approachMethodMethod
מקור מכונןGelman, A., Carlin, J. B., Stern, H. S., Dunson, D. B., Vehtari, A., & Rubin, D. B. (2013). Bayesian Data Analysis (3rd ed.). CRC Press. ISBN: 978-1439840955Cox, D. R. (1958). The regression analysis of binary sequences. Journal of the Royal Statistical Society, Series B, 20(2), 215–242. DOI ↗Kaplan, E. L., & Meier, P. (1958). Nonparametric estimation from incomplete observations. Journal of the American Statistical Association, 53(282), 457–481. DOI ↗
כינוייםBayesian DRA, Bayesian dose-response modeling, Bayesian benchmark dose analysis, BDRlogit model, binomial logistic regression, LRKaplan-Meier analysis, Cox regression, TTE analysis
קשורות333
תקצירBayesian dose-response analysis models the relationship between the level of exposure (dose) to a substance and the magnitude or probability of a biological response, embedding that model in a Bayesian probabilistic framework. Unlike frequentist approaches that yield a single point estimate with confidence intervals, the Bayesian framework produces a full posterior distribution over model parameters, allowing explicit quantification of uncertainty, incorporation of prior scientific knowledge, and principled model averaging. It is widely applied in toxicology, pharmacology, environmental risk assessment, and clinical dose-finding studies.Logistic regression is a statistical method for modeling the probability of a binary outcome (disease present/absent, success/failure) as a function of continuous and categorical predictors. Developed by David Roxbee Cox (1958), it solves the problem of predicting categorical outcomes by applying a logistic transformation to constrain predictions to the [0,1] probability interval, enabling accurate risk stratification, diagnostic prediction, and causal inference in epidemiology, medicine, and social science.Survival analysis is a collection of statistical methods for modeling time from a defined starting point until an event of interest occurs (disease, recovery, death, equipment failure). Kaplan and Meier's nonparametric estimator (1958) and David Cox's proportional hazards model (1972) jointly enabled analysis of censored data—individuals whose event times are unknown because they left the study or were still event-free at follow-up. Indispensable in oncology, cardiology, infectious disease research, engineering reliability, and any field where time-to-event matters.
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ScholarGateהשוואת שיטות: Bayesian Dose-Response Analysis · Logistic Regression · Survival Analysis. אוחזר בתאריך 2026-06-18 מתוך https://scholargate.app/he/compare