Comparer des méthodes
Examinez les méthodes sélectionnées côte à côte ; les lignes qui diffèrent sont mises en évidence.
| SERS× | Résonance des Plasmons de Surface× | |
|---|---|---|
| Domaine | Spectroscopie | Spectroscopie |
| Famille | Process / pipeline | Process / pipeline |
| Année d'origine≠ | 1974 | 1971 |
| Auteur d'origine≠ | Martin Fleischmann | Erich Kretschmann |
| Type≠ | Vibrational spectroscopy technique | Optical technique |
| Source fondatrice≠ | Fleischmann, M., Hendra, P. J., & McQuillan, A. J. (1974). Raman spectra of pyridine adsorbed at a silver electrode. Chemical Physics Letters, 26(2), 163-166. DOI ↗ | Kretschmann, E. (1971). Determination of optical constants of metals by excitation of surface plasmons. Zeitschrift für Physik, 241(4), 313-324. link ↗ |
| Alias≠ | Surface-enhanced Raman scattering, SERS spectroscopy | SPR, surface plasmon, SPR biosensing |
| Apparentées | 3 | 3 |
| Résumé≠ | Surface-Enhanced Raman Spectroscopy (SERS) amplifies weak Raman signals by many orders of magnitude when analyte molecules are adsorbed on specially prepared metal (typically silver or gold) nanostructured surfaces. Discovered by Fleischmann, Hendra, and McQuillan in 1974, SERS enables detection of vibrational signatures of single molecules and ultra-trace contaminants, revolutionizing analytical chemistry and forensics. | Surface Plasmon Resonance (SPR) is a real-time, label-free technique for detecting and monitoring biomolecular interactions at a sensor surface by measuring changes in the refractive index caused by ligand binding. Developed by Kretschmann in 1971 and applied to biosensing by Liedberg, Nylander, and Lundström in 1983, SPR is now a gold standard for measuring binding kinetics (association and dissociation rates) and equilibrium binding constants in protein interactions, antibody-antigen recognition, and drug discovery. |
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