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Étude cas-témoins pragmatique×Étude cas-témoins appariée×
DomaineÉpidémiologieÉpidémiologie
FamilleProcess / pipelineProcess / pipeline
Année d'origine1950s–1960s (classical); pragmatic framing 1967–2000s1950s–1970s
Auteur d'origineEvolved from classical case-control methodology (Dorn, 1954; Cornfield, 1956); pragmatic framing formalized by Schwartz & Lellouch (1967)Brian MacMahon and others; systematised by Schlesselman (1982)
TypeObservational epidemiological study designObservational analytic design
Source fondatriceRothman, K. J., Greenland, S., & Lash, T. L. (2008). Modern Epidemiology (3rd ed.). Lippincott Williams & Wilkins. ISBN: 978-0781755641Rothman, K. J., Greenland, S., & Lash, T. L. (2008). Modern Epidemiology (3rd ed.). Lippincott Williams & Wilkins. ISBN: 978-0781755474
Aliasreal-world case-control study, pragmatic case-control design, effectiveness case-control study, PCCSmatched case-referent study, individually matched case-control, pair-matched case-control, matched case-control design
Apparentées65
RésuméA pragmatic case-control study is an observational design that compares individuals who have developed a disease or outcome (cases) with those who have not (controls), using data collected under routine real-world conditions rather than strictly controlled experimental settings. Exposure histories are reconstructed from clinical records, registries, or administrative databases. The design is chosen when a conventional explanatory case-control study would be impractical, unethical, or too narrow to inform actual clinical or public-health decisions.A matched case-control study is an observational epidemiological design in which each case (a person with the disease or outcome of interest) is paired with one or more controls (persons without the outcome) who share one or more characteristics — such as age, sex, or clinical setting — to control confounding. Exposure history is then compared between cases and their matched controls to estimate the odds ratio of the exposure-disease association.
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ScholarGateComparer des méthodes: Pragmatic case-control study · Matched case-control study. Consulté le 2026-06-17 sur https://scholargate.app/fr/compare