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Étude de cohorte multicentrique×Étude de cohorte prospective×
DomaineÉpidémiologieÉpidémiologie
FamilleProcess / pipelineProcess / pipeline
Année d'origineMid-to-late 20th century (widespread adoption 1970s–1990s)1950s (systematic application); conceptual roots earlier
Auteur d'origineDeveloped incrementally through large collaborative epidemiological projects (e.g., Framingham Heart Study consortium expansions, 1948 onward; EPIC study, 1992)Richard Doll and Austin Bradford Hill (landmark application, 1951-1954); cohort methodology formalised by modern epidemiology textbooks
TypeObservational longitudinal studyObservational longitudinal study design
Source fondatriceRothman, K. J., Greenland, S., & Lash, T. L. (2008). Modern Epidemiology (3rd ed.). Lippincott Williams & Wilkins. ISBN: 978-0781755641Rothman, K. J., Greenland, S., & Lash, T. L. (2008). Modern Epidemiology (3rd ed.). Lippincott Williams & Wilkins. ISBN: 978-0781755641
Aliasmultisite cohort study, multi-centre cohort, collaborative cohort study, pooled cohort studylongitudinal cohort study, prospective follow-up study, incidence study, prospective observational cohort
Apparentées66
RésuméA multicenter cohort study follows defined groups of participants at two or more geographically or institutionally distinct sites over time to estimate incidence, identify risk factors, and quantify associations between exposures and outcomes. By pooling data from multiple centers, it achieves statistical power and population diversity that single-site designs cannot match, making it the workhorse of large-scale epidemiological and clinical research.A prospective cohort study assembles a group of participants who are free of the outcome of interest at baseline, measures their exposures, and then follows them forward in time to record who develops the outcome. By collecting exposure data before outcomes occur, it establishes a clear temporal sequence that supports causal inference — a major advantage over retrospective designs. It is the cornerstone observational method in epidemiology and clinical research.
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ScholarGateComparer des méthodes: Multicenter cohort study · Prospective Cohort Study. Consulté le 2026-06-18 sur https://scholargate.app/fr/compare