Comparer des méthodes

	Goniométrie de l'angle de contact	Gonflement et dégradation
Domaine	Biomatériaux	Biomatériaux
Famille	Process / pipeline	Process / pipeline
Année d'origine	1805	1960
Auteur d'origine	Thomas Young	Wichterle and Lim
Type	Wettability measurement	Kinetic assay
Source fondatrice	Young, T. (1805). An essay on the cohesion of fluids. Philosophical Transactions of the Royal Society, 95, 65-87.	Wichterle, O., & Lim, D. (1960). Hydrophilic gels for biological use. Nature, 185(4706), 117-118.
Alias	sessile drop method, contact angle measurement, wettability analysis	hydrogel swelling, polymer degradation, mass loss assay
Apparentées	3	4
Résumé	Contact angle goniometry is a technique for measuring the wettability of a solid surface by determining the angle at which a liquid droplet meets the surface. Rooted in Thomas Young's thermodynamic analysis from 1805, the method uses optical measurement of droplet profile to quantify surface energy and hydrophilicity. It is indispensable in biomaterials characterization, helping researchers assess whether a scaffold or implant surface will promote or inhibit cell adhesion, protein adsorption, and biointegration.	The swelling and degradation assay measures how biomaterial scaffolds absorb water (swelling) and lose mass over time due to degradation. Developed by Wichterle and Lim in 1960 for hydrogels, the assay is fundamental for characterizing hydrogels, synthetic polymers, and composite scaffolds intended for tissue engineering. The assay provides quantitative data on swelling kinetics (equilibrium water content, swelling ratio), degradation kinetics (mass loss rate, half-life), and mechanisms of degradation (chain scission, enzymatic breakdown).