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Essai Contrôlé Randomisé Adaptatif×Expérience adaptative×
DomainePlans d'expériencesPlans d'expériences
FamilleProcess / pipelineProcess / pipeline
Année d'origine1980s–2000s (formalized; earlier sequential testing roots from Wald, 1947)1940s–1970s (sequential foundations); formalised in clinical and behavioural research by 1980s–2000s
Auteur d'origineDonald Berry and others; foundational adaptive trial methods developed through 1980s–2000s biostatistics literatureAbraham Wald (sequential analysis foundation); expanded by Robbins, Armitage, and others
TypeExperimental design — adaptive variant of RCTExperimental research design
Source fondatriceChow, S.-C., & Chang, M. (2008). Adaptive Design Methods in Clinical Trials. Chapman & Hall/CRC. ISBN: 978-1584887690Chow, S. C., & Chang, M. (2008). Adaptive Design Methods in Clinical Trials. Chapman and Hall/CRC. ISBN: 978-1584886761
AliasAdaptive RCT, Response-adaptive RCT, Adaptive clinical trial, Platform trialadaptive design, response-adaptive randomization, adaptive trial, adaptive randomization
Apparentées65
RésuméAn adaptive randomized controlled trial (adaptive RCT) is an experimental design in which pre-specified rules allow modifications to the trial while it is ongoing — such as changing allocation ratios, dropping underperforming arms, or stopping early for efficacy or futility — based on accumulating interim data. These adaptations are planned before the trial starts and governed by statistical rules to preserve Type I error control and validity.An adaptive experiment is an experimental design in which pre-specified rules allow the protocol to be modified — such as reallocating participants to better-performing arms, stopping early for efficacy or futility, or changing sample size — based on accumulating interim data, while maintaining statistical validity. Adaptive designs are widely used in clinical trials, behavioural economics, and online platform testing to improve efficiency and ethics without sacrificing inferential rigour.
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ScholarGateComparer des méthodes: Adaptive Randomized Controlled Trial · Adaptive Experiment. Consulté le 2026-06-17 sur https://scholargate.app/fr/compare