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| Võimsusanalüüs elulemusuuringutele× | Simulatsioonipõhine võimsusanalüüs (Monte Carlo võimsus)× | |
|---|---|---|
| Valdkond | Statistika | Statistika |
| Perekond | Hypothesis test | Hypothesis test |
| Tekkeaasta≠ | 1981 | 2011 |
| Looja≠ | — | Arnold et al. (2011); Green & MacLeod (2016) for mixed-model extension |
| Tüüp≠ | Sample size determination for survival outcomes | Simulation-based (Monte Carlo) |
| Algallikas≠ | Schoenfeld, D. A. (1981). The asymptotic properties of nonparametric tests for comparing survival distributions. Biometrika, 68(1), 316–319. DOI ↗ | Arnold, B.F. et al. (2011). Simulation Methods to Estimate Design Power: An Overview for Applied Research. BMC Medical Research Methodology, 11, 94. DOI ↗ |
| Rööpnimetused | log-rank power analysis, cox regression power analysis, survival power analysis, Sağkalım Analizi Güç Analizi | Monte Carlo power analysis, Monte Carlo simulation power, MC power, Simülasyon Tabanlı Güç Analizi (Monte Carlo Power) |
| Seotud | 6 | 6 |
| Kokkuvõte≠ | Power analysis for survival studies determines how many participants — and how many observed events — are required so that a log-rank test or Cox regression has a sufficient probability of detecting a clinically meaningful difference in survival between groups. The foundational formulas were derived by Schoenfeld (1981) and Lachin (1981) and remain the standard approach in clinical trial planning. | Simulation-based power analysis estimates the statistical power and required sample size of a study by repeating a full analysis pipeline thousands of times on artificially generated data. Because it relies on Monte Carlo simulation rather than closed-form equations, it is applicable to designs — mixed models, complex measurement structures, non-standard outcomes — where analytical power formulas do not exist. The approach was systematically described for applied research by Arnold et al. in 2011, and the mixed-model implementation via the SIMR package was formalised by Green and MacLeod in 2016. |
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