Medication Understanding and Use Self-Efficacy Scale (MUSE-S)

The Medication Understanding and Use Self-Efficacy Scale (MUSE-S) is a brief, patient-centered self-report measure assessing both knowledge and confidence regarding medication use. Developed by Kripalani and colleagues at Emory University in 2009, the MUSE-S evaluates whether patients understand their medications (what they are for, how to take them, important side effects) and feel confident managing them in daily life. This dual focus on knowledge and self-efficacy makes the MUSE-S particularly valuable for identifying education gaps, assessing health literacy barriers to medication adherence, and evaluating outcomes of medication counseling or education interventions.