Process / pipelinePharmaceutical Chemistry

Arrhenius Stability Testing

Arrhenius stability testing predicts pharmaceutical product shelf-life by conducting accelerated degradation studies at elevated temperatures and using the Arrhenius equation to extrapolate to storage conditions. Based on Svante Arrhenius's 1889 equation relating reaction rate to temperature, this method is regulatory standard for establishing expiration dates.

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Sources

  1. Arrhenius, S. (1889). Über die Reaktionsgeschwindigkeit bei der Inversion von Rohrzucker durch Säuren. Zeitschrift für Physikalische Chemie, 4, 226-248. link
  2. Carstensen, J. T. (1995). Drug stability: principles and practices. New York: Marcel Dekker. link

Related methods

ScholarGateArrhenius Stability (Arrhenius Stability Testing). Retrieved 2026-06-04 from https://scholargate.app/en/pharmacology/arrhenius-stability