Endometriosis Health Profile-30
Endometriosis Health Profile-30 (EHP-30) · Also known as: EHP-30, EHP-Core30
The Endometriosis Health Profile-30 (EHP-30) is a disease-specific quality-of-life questionnaire comprising 30 core items measuring the multidimensional impact of endometriosis on women's health and well-being. Developed by Jones and colleagues in 2001, the EHP-30 assesses five core domains: pain, emotional well-being, social support, sexual relations, and work/study impacts. Optional modular items address specific endometriosis-related concerns (infertility, medical side effects, treatment). It is the gold-standard endometriosis-specific outcome measure used in clinical trials and endometriosis research.
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When to use it
The EHP-30 is appropriate at initial endometriosis diagnosis to establish quality-of-life baseline across all domains, guiding personalized treatment planning. It is valuable for monitoring multidimensional response to endometriosis treatments (medical therapy, surgical management, pain management, psychological intervention), with serial administration enabling responsive outcome tracking. The EHP-30 is standard in endometriosis clinical trials and increasingly adopted in clinical practice. It is particularly valuable for women weighing treatment options, as domain scores illuminate disease burden across life domains and can guide treatment priorities.
Strengths & limitations
- Disease-specific design developed through extensive qualitative research with women with endometriosis, ensuring comprehensive and relevant item content.
- Five-domain structure capturing pain, emotion, social, sexual, and occupational impacts—distinctly multidimensional compared to pain-only measures.
- 0-100 domain scoring enables easy interpretation and comparison across domains and time points.
- Highly responsive to treatment; EHP-30 scores improve significantly following effective endometriosis interventions.
- Optional modular items (infertility, medical side effects) can be added to address individual patient concerns.
- Gold-standard endometriosis outcome measure; extensively used in international endometriosis research and clinical practice.
- Requires women to be previously diagnosed with endometriosis; not suitable for screening or case-finding.
- Does not assess all relevant endometriosis impacts (e.g., relationship/partnership strain beyond sexual relations, family planning stress, healthcare navigation burden).
- Relies entirely on self-report; response bias possible, particularly regarding emotional and sexual domains.
- Modular items are not comprehensive; additional items may be needed for specific populations (e.g., adolescents, women pursuing fertility treatment).
Frequently asked
Does a high Pain domain score on EHP-30 mean I need surgery?
High Pain domain scores reflect significant pain-related quality-of-life impact, but surgery decision depends on multiple factors: response to medical therapy, surgical history, fertility goals, surgeon expertise, and individual preferences. Many women improve with medical management alone. Discuss surgical options with your endometriosis specialist.
Can EHP-30 be used to diagnose endometriosis?
No. The EHP-30 is only for women with confirmed endometriosis diagnosis. It measures quality-of-life impact, not diagnostic status. Endometriosis diagnosis requires clinical assessment, imaging, and sometimes diagnostic laparoscopy.
What improvements in EHP-30 score indicate effective treatment?
Clinical meaningful improvement in endometriosis trials typically shows 10-20 point reductions in domain scores or total score. However, individual expectations vary. Discuss with your clinician what score improvements would represent meaningful benefit for your priorities and goals.
Are EHP-30 scores better or worse after hysterectomy?
EHP-30 scores often improve post-hysterectomy in women with severe endometriosis, particularly Pain domain scores. However, some women experience persistent sexual dysfunction or other quality-of-life impacts. Hysterectomy decision requires careful discussion of risks/benefits and realistic outcome expectations.
Sources
- Jones, G. L., Kennedy, S. H., Barnard, A., Wong, J., & Jenkinson, C. (2001). Development of an endometriosis quality-of-life instrument: The Endometriosis Health Profile-30. Obstetrics & Gynecology, 98(2), 258-264. DOI: 10.1097/00006250-200108000-00014 ↗
- Jones, G. L., Kennedy, S. H., Jenkinson, C., & Endometriosis Consortium (2002). Evaluating the responsiveness of the Endometriosis Health Profile Questionnaire: comparing responses from women with endometriosis to gynaecological controls. Human Reproduction, 17(9), 2464-2468. link ↗
How to cite this page
ScholarGate. (2026, June 3). Endometriosis Health Profile-30 (EHP-30). ScholarGate. https://scholargate.app/en/obstetrics-gynecology/endometriosis-health-profile
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