Process / pipelineNeurological Headache and Pain
Headache Impact Test-6
The HIT-6 is a brief, validated measure of headache impact on daily functioning and quality of life. Developed by Mark Kosinski and colleagues in 2003, this 6-item questionnaire quantifies how headache (migraine or other types) affects work, social activities, sleep, and emotional well-being. It is widely used in headache research, clinical trials, and practice to assess disease burden and treatment benefit.
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Sources
- Kosinski, M., Bayliss, M. S., Bjorner, J. B., Ware, J. E., Garber, W. H., Batenhorst, A., & Tepper, S. (2003). A six-item short-form survey for measuring headache impact: The HIT-6. Quality of Life Research, 12(8), 963-974. DOI: 10.1023/A:1026119331193 ↗
- Yang, M., Rendas-Baum, R., Varon, S. F., & Kosinski, M. (2011). Validation of the Headache Impact Test (HIT-6) across episodic and chronic migraine. Cephalalgia, 31(3), 357-367. DOI: 10.1177/0333102410379890 ↗
- Lipton, R. B., Dodick, D. W., Silberstein, S. D., Saper, J. R., Aurora, S. K., Pearlman, S. H., ... & Goadsby, P. J. (2007). Topiramate for episodic migraine prevention: A randomized, double-blind, placebo-controlled trial. Headache, 47(2), 170-180. DOI: 10.1111/j.1526-4610.2007.00684.x ↗