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Double-Blind Single-Subject Experimental Design

A double-blind single-subject experimental design applies systematic masking — concealing treatment assignment from both the participant and the outcome assessor — within a within-person repeated-measures framework. It is used when researchers need strong causal inference about an intervention's effect on a single individual while guarding against placebo responses and observer bias. Particularly prominent in pharmacological, behavioral, and clinical rehabilitation research.

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Sources

  1. Kazdin, A. E. (2011). Single-Case Research Designs: Methods for Clinical and Applied Settings (2nd ed.). Oxford University Press. ISBN: 978-0195341881
  2. Barlow, D. H., Nock, M. K., & Hersen, M. (2009). Single Case Experimental Designs: Strategies for Studying Behavior Change (3rd ed.). Pearson. ISBN: 978-0205474554

Related methods

ScholarGateDouble-blind single-subject experimental design (Double-Blind Single-Subject Experimental Design). Retrieved 2026-06-04 from https://scholargate.app/en/experimental-design/double-blind-single-subject-experimental-design