Time-series eQTL analysis
Time-series eQTL analysis identifies genetic variants (eQTLs) whose effect on gene expression changes over time or across developmental stages. By combining longitudinal RNA-seq data with individual genotypes, the method captures how the same SNP can activate, silence, or reshape gene regulation at different time points — revealing the temporal architecture of the genome's regulatory program in processes such as differentiation, disease progression, and environmental response.
Source record
Citations copied verbatim from the method’s source record. No claim-level verification is inferred from them.
- Fair, B. J., et al. (2020). Gene expression variability in human and chimpanzee populations share common determinants. eLife, 9, e59929. · URL
- Strober, B. J., et al. (2019). Dynamic genetic regulation of gene expression during cellular differentiation. Science, 364(6447), 1287–1290. · URL
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Related methods
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