Radioimmunoassay
Radioimmunoassay (RIA) is a highly sensitive, quantitative laboratory technique that measures the concentration of a specific antigen — such as a hormone, drug, or pathogen-derived protein — in a biological sample by exploiting competitive binding between a radiolabelled antigen and the sample antigen for a limited supply of specific antibody. Developed in the late 1950s, RIA is widely used in veterinary science, endocrinology, pharmacology, and clinical diagnostics.
Source record
Citations copied verbatim from the method’s source record. No claim-level verification is inferred from them.
- Yalow, R. S., & Berson, S. A. (1960). Immunoassay of endogenous plasma insulin in man. Journal of Clinical Investigation, 39(7), 1157–1175. · DOI 10.1172/JCI104130
- Sauer, M. J. (Ed.). (1981). Radioimmunoassay in Basic and Clinical Pharmacology. Springer. · URL
Curated claims
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Related methods
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