Network-based microbiome diversity analysis
Network-based microbiome diversity analysis integrates graph-theoretic co-occurrence network inference with classical alpha- and beta-diversity metrics to characterize the structural organization of microbial communities. Rather than treating taxa as independent entities, the method models pairwise microbial associations as edges in a network, enabling identification of keystone taxa, community modules, and ecological interaction patterns that simple diversity indices cannot detect.
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- Friedman, J., & Alm, E. J. (2012). Inferring correlation networks from genomic survey data. PLoS Computational Biology, 8(9), e1002687. · DOI 10.1371/journal.pcbi.1002687
- Faust, K., & Raes, J. (2012). Microbial interactions: from networks to models. Nature Reviews Microbiology, 10(8), 538–550. · DOI 10.1038/nrmicro2832
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