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Multicenter Case-Crossover Design/Evidence
Method evidence record

Multicenter Case-Crossover Design

The multicenter case-crossover design is an observational epidemiological method that investigates whether brief, transient exposures trigger acute health events by comparing each case's exposure just before the event to their own exposure during matched control periods — with data collected from two or more independent clinical or geographic sites to increase power, external validity, and the ability to detect site-level effect modification.

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Source record

Citations copied verbatim from the method’s source record. No claim-level verification is inferred from them.

Multicenter Case-Crossover Epidemiological Study
Taxonomic method record · process-pipeline / epidemiology
  • Maclure, M. (1991). The case-crossover design: A method for studying transient effects on the risk of acute events. American Journal of Epidemiology, 133(2), 144–153. · DOI 10.1093/oxfordjournals.aje.a115853
  • Case-crossover study. Wikipedia. · URL
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Related methods

Generated from the method graph and shown as machine-suggested relations — no evidence claim is inferred.

Taxonomic bucketCase-control studymachine-suggested · Relational suggestion, not evidence.Taxonomic bucketCase-crossover designmachine-suggested · Relational suggestion, not evidence.Same method familyCase-Time-Control Designmachine-suggested · Relational suggestion, not evidence.Taxonomic bucketMulticenter cohort studymachine-suggested · Relational suggestion, not evidence.Taxonomic bucketNested case-controlmachine-suggested · Relational suggestion, not evidence.

Evidence status

Sources recorded, not reviewed

Bibliographic sources are present. Claim-level evidence review has not been performed.

Sources

2 recorded citations, copied from the method source record.

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