Meta-analytic Nested Case-Control
Meta-analytic nested case-control analysis combines the efficiency advantages of the nested case-control design — in which cases and matched controls are sampled from a defined cohort — with the statistical power and generalisability gained by pooling estimates from multiple such studies. This approach is especially valuable in chronic-disease epidemiology where individual studies are often underpowered to detect modest exposure-outcome associations.
Source record
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- Rothman, K. J., Greenland, S., & Lash, T. L. (2008). Modern Epidemiology (3rd ed.). Lippincott Williams & Wilkins. · ISBN 978-0781755641
- Hamling, J., Lee, P., Weitkunat, R., & Ambuhl, M. (2008). Facilitating meta-analyses by deriving relative effect and precision estimates for alternative comparisons from a set of estimates presented by exposure level or disease category. Statistics in Medicine, 27(7), 954–970. · DOI 10.1002/sim.3013
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