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ALSFRS-R/Evidence
Method evidence record

ALSFRS-R

The ALSFRS-R is a 12-item clinician-administered functional rating scale designed to assess disease progression and functional status in amyotrophic lateral sclerosis (ALS). Introduced by Cedarbaum and colleagues in 1999, it expands upon the original ALSFRS by incorporating respiratory function assessment. It is the primary outcome measure in ALS clinical trials and routine clinical monitoring, providing quantitative tracking of disease decline that predicts survival and guides management decisions.

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Source record

Citations copied verbatim from the method’s source record. No claim-level verification is inferred from them.

ALS Functional Rating Scale Revised
Taxonomic method record · process-pipeline / neurology
  • Cedarbaum, J. M., Stambler, N., Malta, E., Fuller, C., Hilt, D., Thurmond, B., & Nakanishi, A. (1999). The ALSFRS-R: A revised ALS functional rating scale that incorporates assessments of respiratory function. Journal of the Neurological Sciences, 169(1-2), 13-21. · DOI 10.1016/S0022-510X(99)00210-5
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Curated claims

Claims persisted in the evidence ledger, each with its own assessment.

No curated claims yet

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Related methods

Generated from the method graph and shown as machine-suggested relations — no evidence claim is inferred.

Same method familyModified Rankin Scalemachine-suggested · Relational suggestion, not evidence.Same method familyMSQOL-54machine-suggested · Relational suggestion, not evidence.Same method familyMSWS-12machine-suggested · Relational suggestion, not evidence.Same method familySS-QoLmachine-suggested · Relational suggestion, not evidence.

Evidence status

Sources recorded, not reviewed

Bibliographic sources are present. Claim-level evidence review has not been performed.

Sources

1 recorded citation, copied from the method source record.

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