Process / pipelineClinical / epidemiology
Meta-analytic Diagnostic Accuracy Study
A meta-analytic diagnostic accuracy study systematically identifies and pools sensitivity and specificity data from multiple primary diagnostic test accuracy studies. Using the bivariate or hierarchical summary ROC (HSROC) model, it produces a joint summary of a test's ability to correctly classify diseased and non-diseased individuals across diverse clinical settings, accounting for the inherent trade-off between sensitivity and specificity.
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Sources
- Reitsma, J. B., Glas, A. S., Rutjes, A. W., Scholten, R. J., Bossuyt, P. M., & Zwinderman, A. H. (2005). Bivariate analysis of sensitivity and specificity produces informative summary measures in diagnostic reviews. Journal of Clinical Epidemiology, 58(10), 982–990. DOI: 10.1016/j.jclinepi.2005.02.022 ↗
- Macaskill, P., Gatsonis, C., Deeks, J. J., Harbord, R. M., & Takwoingi, Y. (2010). Analysing and Presenting Results. In J. J. Deeks, P. M. Bossuyt, & C. Gatsonis (Eds.), Cochrane Handbook for Systematic Reviews of Diagnostic Test Accuracy. The Cochrane Collaboration. link ↗