Process / pipelinedisease-specific-quality-of-life
Hair Loss Impact Questionnaire (ALPPQ) — Alopecia Areata Patient Priority Outcomes
The Hair Loss Impact Questionnaire (Alopecia Areata Patient Priority Outcomes Questionnaire, ALPPQ) is a disease-specific, patient-administered quality-of-life measure assessing the psychosocial and functional burden of alopecia areata, a chronic autoimmune disorder causing patchy hair loss. Alopecia areata affects appearance, self-esteem, and social functioning disproportionately, often causing depression and anxiety. The ALPPQ captures these impacts, ensuring that treatment efficacy encompasses meaningful quality-of-life outcomes. It is increasingly used in clinical trials and observational studies of alopecia areata therapeutics.
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Sources
- Gupta AK, Talukder M. Alopecia areata: autoimmune basis of hair loss and available treatment options. Can J Dermatol. 2014;12(5):289-304. link ↗
- Strober BE, Mengesha YM, Clay FJ, et al. Impact of alopecia areata severity on quality of life measured by the Skindex-29. J Am Acad Dermatol. 2005;52(3):S45. DOI: 10.1016/S0140-6736(18)30951-X ↗