Process / pipelineComputational biomechanics
FEA Bone Remodeling
Finite element analysis (FEA) for bone remodeling predicts how bone tissue density and architecture adapt to changes in mechanical loading over time. Pioneered by Rik Huiskes and Donald Carter in the 1980s, this computational approach integrates stress analysis with biophysical remodeling rules to simulate the long-term response of bone to disease, aging, or surgical intervention.
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Sources
- Huiskes, R., Weinans, H., Grootenboer, H. J., Dalstra, M., Fudala, B., & Slooff, T. J. (1987). Adaptive bone-remodeling theory applied to prosthetic-design analysis. Journal of Biomechanics, 20(11-12), 1135-1150. DOI: 10.1016/0021-9290(87)90030-3 ↗
- Carter, D. R., Fyhrie, D. P., & Whalen, R. T. (1987). Trabecular bone density and loading history: regulation of stress-induced bone loss. Journal of Biomechanics, 20(9), 785-794. DOI: 10.1016/0021-9290(87)90058-3 ↗