Process / pipelineBioinformatics / omics
Metabolomics Analysis — Metabolome Profiling
Metabolomics analysis is the large-scale, systematic measurement of small-molecule metabolites in a biological sample to characterise the metabolome — the complete set of metabolic intermediates and products present under defined conditions. By coupling high-throughput analytical platforms such as mass spectrometry (MS) or nuclear magnetic resonance (NMR) spectroscopy with multivariate statistics and pathway databases, metabolomics bridges the genotype–phenotype gap and captures the downstream functional output of genes, transcripts, and proteins in real time.
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Sources
- Fiehn, O. (2002). Metabolomics — the link between genotypes and phenotypes. Plant Molecular Biology, 48(1-2), 155–171. link ↗
- Wishart, D. S., et al. (2022). HMDB 5.0: the Human Metabolome Database for 2022. Nucleic Acids Research, 50(D1), D622–D631. DOI: 10.1093/nar/gkab1062 ↗
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Referenced by
Bayesian Metabolomics AnalysisDifferential Metabolomics AnalysisMulti-omics metabolomics analysisMulti-omics microbiome diversity analysisMulti-omics proteomics analysisNetwork-based metabolomics analysisPathway Enrichment AnalysisProteomics AnalysisSingle-cell metabolomics analysisTime-series metabolomics analysisTime-series proteomics analysis