Process / pipelineBioinformatics / omics
Genome-Wide Association Study in Educational Research
A genome-wide association study (GWAS) applied to educational research scans millions of single-nucleotide polymorphisms (SNPs) across the human genome to identify genetic variants statistically associated with educational outcomes such as years of schooling, degree attainment, or cognitive test scores. Large consortia — most prominently the Social Science Genetic Association Consortium — have conducted landmark studies in hundreds of thousands to millions of individuals, establishing GWAS as the principal genomic tool for understanding the heritable architecture of educational phenotypes.
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Sources
- Okbay, A., Turley, P., Georgios, K., et al. (2022). Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals. Nature Genetics, 54(4), 437–449. link ↗
- Lee, J. J., Wedow, R., Okbay, A., et al. (2018). Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals. Nature Genetics, 50(8), 1112–1121. link ↗