Methoden vergleichen
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| Prospektive Evaluation von Screening-Tests× | Studiendesign zur diagnostischen Genauigkeit× | |
|---|---|---|
| Fachgebiet≠ | Epidemiologie | Klinische Forschung |
| Familie | Process / pipeline | Process / pipeline |
| Entstehungsjahr≠ | 1980s–2000s (STARD 2003, updated 2015) | 2003-2015 |
| Urheber≠ | Formalized through diagnostic accuracy methodology (Sackett, Haynes, Tugwell; STARD initiative) | Bossuyt, Reitsma, and STARD group (2003); clinical epidemiology pioneers |
| Typ≠ | Prospective observational study design | Research Design |
| Wegweisende Quelle≠ | Bossuyt, P. M., Reitsma, J. B., Bruns, D. E., et al. (2015). STARD 2015: An Updated List of Essential Items for Reporting Diagnostic Accuracy Studies. BMJ, 351, h5527. DOI ↗ | Bossuyt, P. M., Reitsma, J. B., Bruns, D. E., Gatsonis, C. A., Glasziou, P. P., Irwig, L. M., ... & de Vet, H. C. (2003). Towards complete and accurate reporting of studies of diagnostic accuracy: the STARD initiative. Annals of Internal Medicine, 138(1), 40–44. DOI ↗ |
| Aliasnamen | prospective diagnostic accuracy study, prospective test performance study, forward-looking screening validation, prospective DTA study | diagnostic accuracy study, test accuracy, STARD, diagnostic evaluation |
| Verwandt≠ | 6 | 2 |
| Zusammenfassung≠ | A prospective screening test evaluation enrolls participants before the outcome is known, applies the screening test and the reference standard in temporal sequence, and measures how accurately the test identifies individuals with or without the target condition. This forward-looking design minimizes workup bias and spectrum bias, producing estimates of sensitivity, specificity, and predictive values that are more generalizable to real clinical or public-health screening contexts than retrospective alternatives. | A diagnostic accuracy study evaluates how well a new diagnostic test (or biomarker, imaging modality, clinical assessment) detects the presence or absence of disease compared to a reference standard (gold standard). Standardized since 2003 by the STARD (Standards for Reporting of Diagnostic Accuracy Studies) initiative, diagnostic accuracy studies are fundamental to clinical medicine, determining whether and how new tests can improve patient diagnosis and treatment. |
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