Methoden vergleichen

	EDSS: Kurtzke Expanded Disability Status Scale	MDS-UPDRS	NIHSS: National Institutes of Health Stroke Scale
Fachgebiet	Neurologie	Neurologie	Neurologie
Familie	Process / pipeline	Process / pipeline	Process / pipeline
Entstehungsjahr	1983	2008	1989
Urheber	John F. Kurtzke	Christopher G. Goetz and Movement Disorder Society	Thomas Brott and NIH Stroke Study Group
Typ	Clinician-rated	Clinician-rated	Clinician-rated
Wegweisende Quelle	Kurtzke, J. F. (1983). Rating neurologic impairment in multiple sclerosis: An expanded disability status scale (EDSS). Neurology, 33(11), 1444-1452.	Goetz, C. G., et al. (2008). Movement Disorder Society-sponsored revision of the Unified Parkinson's Disease Rating Scale (MDS-UPDRS): Scale presentation and clinimetric testing results. Movement Disorders, 23(15), 2129-2170.	Brott, T., Adams, H. P., Olinger, C. P., et al. (1989). Measurements of acute cerebral infarction: A clinical examination scale. Stroke, 20(7), 864-870.
Aliasnamen	Expanded Disability Status Scale	UPDRS	NIH Stroke Scale
Verwandt	4	5	5
Zusammenfassung	The EDSS is the most widely used clinical disability rating scale in multiple sclerosis research and practice. Developed by John Kurtzke in 1983, it provides a 0-10 ordinal scale capturing disease severity across eight neurological functional systems and functional status. The EDSS remains the primary endpoint in MS clinical trials and longitudinal cohort studies, with decades of prognostic and comparative data worldwide.	The MDS-UPDRS is the gold-standard clinician-administered rating scale for assessing motor and non-motor manifestations of Parkinson's disease. Developed by the Movement Disorder Society in 2008 to enhance the original UPDRS, it measures disease severity across daily living, motor function, and treatment complications. Used globally in clinical trials, longitudinal cohort studies, and routine neurological practice.	The NIHSS is the standard acute stroke severity assessment tool used in emergency departments, stroke centers, and clinical trials worldwide. Developed by the NIH Stroke Study Group in 1989, the 15-item scale provides rapid, reproducible quantification of acute neurological deficit from ischemic or hemorrhagic stroke. NIHSS scores inform thrombolytic and thrombectomy eligibility, predict outcomes, and serve as primary endpoint in stroke intervention trials.