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| EDSS: Kurtzke Expanded Disability Status Scale× | NIHSS: National Institutes of Health Stroke Scale× | |
|---|---|---|
| Fachgebiet | Neurologie | Neurologie |
| Familie | Process / pipeline | Process / pipeline |
| Entstehungsjahr≠ | 1983 | 1989 |
| Urheber≠ | John F. Kurtzke | Thomas Brott and NIH Stroke Study Group |
| Typ | Clinician-rated | Clinician-rated |
| Wegweisende Quelle≠ | Kurtzke, J. F. (1983). Rating neurologic impairment in multiple sclerosis: An expanded disability status scale (EDSS). Neurology, 33(11), 1444-1452. DOI ↗ | Brott, T., Adams, H. P., Olinger, C. P., et al. (1989). Measurements of acute cerebral infarction: A clinical examination scale. Stroke, 20(7), 864-870. DOI ↗ |
| Aliasnamen | Expanded Disability Status Scale | NIH Stroke Scale |
| Verwandt≠ | 4 | 5 |
| Zusammenfassung≠ | The EDSS is the most widely used clinical disability rating scale in multiple sclerosis research and practice. Developed by John Kurtzke in 1983, it provides a 0-10 ordinal scale capturing disease severity across eight neurological functional systems and functional status. The EDSS remains the primary endpoint in MS clinical trials and longitudinal cohort studies, with decades of prognostic and comparative data worldwide. | The NIHSS is the standard acute stroke severity assessment tool used in emergency departments, stroke centers, and clinical trials worldwide. Developed by the NIH Stroke Study Group in 1989, the 15-item scale provides rapid, reproducible quantification of acute neurological deficit from ischemic or hemorrhagic stroke. NIHSS scores inform thrombolytic and thrombectomy eligibility, predict outcomes, and serve as primary endpoint in stroke intervention trials. |
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