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| Radiomik× | CT Iterativ Rekonstruktion× | OCT Angiografi× | PET kinetisk modellering× | |
|---|---|---|---|---|
| Fagområde | Medicinsk billeddiagnostik | Medicinsk billeddiagnostik | Medicinsk billeddiagnostik | Medicinsk billeddiagnostik |
| Familie | Process / pipeline | Process / pipeline | Process / pipeline | Process / pipeline |
| Oprindelsesår≠ | 2012 | 1974 | 2012 | 1983 |
| Ophavsperson≠ | Philippe Lambin | Richard Gordon | Yali Jia | Christoph Patlak |
| Type≠ | Machine learning-based texture and morphology analysis | Algorithm for tomographic image reconstruction | Optical imaging technique for vasculature visualization | Mathematical framework for tracer kinetics in PET imaging |
| Oprindelig kilde≠ | Lambin, P., Rios-Velazquez, E., Leijenaar, R., et al. (2012). Radiomics: extracting more information from medical images using advanced feature analysis. Nature Reviews Clinical Oncology, 9(12), 676-684. DOI ↗ | Gordon, R., Bender, R., Herman, G. T. (1974). Algebraic reconstruction techniques (ART) for three-dimensional electron microscopy and X-ray photography. Journal of Theoretical Biology, 29(3), 471-481. link ↗ | Jia, Y., Tan, O., Tokayer, J., et al. (2012). Split-spectrum amplitude-decorrelation angiography with optical coherence tomography. Optics Express, 20(4), 4710-4725. DOI ↗ | Patlak, C. S., Blasberg, R. G., Fenstermacher, J. D. (1983). Graphical evaluation of blood-to-brain transfer constants from multiple-time uptake data. Journal of Cerebral Blood Flow & Metabolism, 3(1), 1-7. DOI ↗ |
| Aliasser≠ | texture analysis, radiomics analysis, quantitative imaging biomarkers | MBIR, ASIR, IR-CT, statistical reconstruction | OCTA, OCT-A | PET pharmacokinetics, Dynamic PET, PET compartmental modeling |
| Relaterede | 5 | 5 | 5 | 5 |
| Resumé≠ | Radiomics is a computational methodology that extracts large numbers of quantitative features from medical images (CT, MRI, PET) using automated image analysis and machine learning to discover imaging biomarkers associated with disease phenotype, prognosis, and treatment response. Developed by Lambin, Gillies, and colleagues in 2012, radiomics aims to decode the biology underlying visible imaging patterns, enabling personalized medicine through image-based phenotyping. It has emerged as a powerful tool in oncology for tumor characterization, prognosis prediction, and therapy response assessment. | CT Iterative Reconstruction (IR) is a computational technique that reconstructs tomographic images from raw X-ray projection data by iteratively refining an estimate of tissue attenuation until it matches the measured projections. Developed from algebraic reconstruction techniques pioneered by Gordon in 1974, iterative reconstruction has revolutionized clinical CT by enabling high-quality images at reduced radiation dose. Variants such as Adaptive Statistical Iterative Reconstruction (ASIR) and Model-Based Iterative Reconstruction (MBIR) are now standard on modern CT scanners. | Optical Coherence Tomography Angiography (OCTA) is a non-invasive imaging technique that visualizes the microvasculature in the retina and choroid by detecting motion contrast from flowing blood. Developed by Jia and colleagues in 2012, OCTA uses repeated OCT scans of the same tissue location to identify blood flow based on the decorrelation signal. It has become a critical diagnostic tool in ophthalmology for detecting retinal and macular diseases without requiring fluorescein injection. | PET kinetic modeling is a quantitative analysis technique that tracks the temporal behavior of radioactive tracers in tissue to extract physiological parameters such as blood flow, metabolic rate, and receptor density. Established by Patlak, Logan, and Gunn in the 1980s and 1990s, kinetic modeling transforms raw PET time-activity curves into interpretable biological measures. It is widely used in neurology, oncology, and cardiology to assess disease severity, treatment response, and regional tissue function. |
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