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Koalescensteori×Admixture Analysis×Rekonstruktion af forfædres tilstand×
FagområdeGenetikGenetikGenetik
FamilieProcess / pipelineProcess / pipelineProcess / pipeline
Oprindelsesår198220091991
OphavspersonJohn KingmanDavid Alexander & Jonathan NovembreWayne Maddison
TypeStochastic process modelClustering and inference methodInference method
Oprindelig kildeKingman, J. F. C. (1982). The coalescent. Stochastic Processes and their Applications, 13(3), 235–248. DOI ↗Alexander, D. H., Novembre, J., & Lange, K. (2009). Fast model-based estimation of ancestry in unrelated individuals. Genome Research, 19(9), 1655–1664. DOI ↗Maddison, W. P. (1991). Squared-change parsimony reconstructions of ancestral states for continuous-valued characters on a phylogenetic tree. Systematic Zoology, 40(3), 308–314. DOI ↗
AliasserKingman Coalescent, n-coalescentPopulation structure inference, Ancestry analysis, ADMIXTUREASR, Ancestral character reconstruction, Trait reconstruction
Relaterede443
ResuméCoalescent theory is a probabilistic framework that traces the genealogical history of DNA sequences backward in time to their most recent common ancestor. Developed by John Kingman in 1982, this method forms the foundation of modern population genetics, enabling researchers to understand demographic events, estimate genetic parameters, and reconstruct evolutionary histories from modern genetic data.Admixture analysis is a population genetics method that infers population structure and individual ancestry from multilocus genotype data. Originally developed by Pritchard, Stephens, and Donnelly (2000) and refined by Alexander, Novembre, and Lange (2009), admixture analysis reveals how genetic variation is distributed among populations and estimates the ancestry fractions of admixed individuals. This technique is essential for understanding human evolutionary history, detecting population stratification in genetic studies, and inferring individual ancestry.Ancestral state reconstruction (ASR) is a phylogenetic method that infers the character states (trait values or evolutionary features) of extinct ancestors by analyzing patterns of variation in extant (living) species. Developed by Wayne Maddison and colleagues in the 1990s, ASR uses the phylogenetic tree and observed trait variation in living species to estimate what ancestors possessed, enabling researchers to trace the evolutionary history of morphological, behavioral, ecological, and genomic traits.
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ScholarGateSammenlign metoder: Coalescent Theory · Admixture Analysis · Ancestral State Reconstruction. Hentet 2026-06-19 fra https://scholargate.app/da/compare