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Escala de Discapacitat Expandida EDSS: Kurtzke×MDS-UPDRS×MSFC: Multiple Sclerosis Functional Composite×NIHSS: National Institutes of Health Stroke Scale×
CampNeurologiaNeurologiaNeurologiaNeurologia
FamíliaProcess / pipelineProcess / pipelineProcess / pipelineProcess / pipeline
Any d'origen1983200819991989
Autor originalJohn F. KurtzkeChristopher G. Goetz and Movement Disorder SocietyGary Cutter, Richard Rudick, and NMSS ConsortiumThomas Brott and NIH Stroke Study Group
TipusClinician-ratedClinician-ratedClinician-administered performance testClinician-rated
Font seminalKurtzke, J. F. (1983). Rating neurologic impairment in multiple sclerosis: An expanded disability status scale (EDSS). Neurology, 33(11), 1444-1452. DOI ↗Goetz, C. G., et al. (2008). Movement Disorder Society-sponsored revision of the Unified Parkinson's Disease Rating Scale (MDS-UPDRS): Scale presentation and clinimetric testing results. Movement Disorders, 23(15), 2129-2170. DOI ↗Cutter, G. R., Baier, M. L., Rudick, R. A., et al. (1999). Development of a multiple sclerosis functional composite as a clinical trial outcome measure. Multiple Sclerosis, 5(4), 244-250. DOI ↗Brott, T., Adams, H. P., Olinger, C. P., et al. (1989). Measurements of acute cerebral infarction: A clinical examination scale. Stroke, 20(7), 864-870. DOI ↗
ÀliesExpanded Disability Status ScaleUPDRSMS Functional CompositeNIH Stroke Scale
Relacionats4545
ResumThe EDSS is the most widely used clinical disability rating scale in multiple sclerosis research and practice. Developed by John Kurtzke in 1983, it provides a 0-10 ordinal scale capturing disease severity across eight neurological functional systems and functional status. The EDSS remains the primary endpoint in MS clinical trials and longitudinal cohort studies, with decades of prognostic and comparative data worldwide.The MDS-UPDRS is the gold-standard clinician-administered rating scale for assessing motor and non-motor manifestations of Parkinson's disease. Developed by the Movement Disorder Society in 2008 to enhance the original UPDRS, it measures disease severity across daily living, motor function, and treatment complications. Used globally in clinical trials, longitudinal cohort studies, and routine neurological practice.The Multiple Sclerosis Functional Composite (MSFC) is an objective, performance-based assessment of MS-related disability capturing three key functional domains: lower extremity mobility, upper extremity coordination, and cognitive/processing speed. Developed in 1999 by the National MS Society and adopted widely in clinical trials, the MSFC provides quantifiable endpoints complementing the Expanded Disability Status Scale (EDSS). The three-component design addresses EDSS limitations by including cognition and standardizing measurement via timed tasks.The NIHSS is the standard acute stroke severity assessment tool used in emergency departments, stroke centers, and clinical trials worldwide. Developed by the NIH Stroke Study Group in 1989, the 15-item scale provides rapid, reproducible quantification of acute neurological deficit from ischemic or hemorrhagic stroke. NIHSS scores inform thrombolytic and thrombectomy eligibility, predict outcomes, and serve as primary endpoint in stroke intervention trials.
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ScholarGateCompara mètodes: EDSS · MDS-UPDRS · MSFC · NIHSS. Recuperat el 2026-06-19 de https://scholargate.app/ca/compare