Compara mètodes

	Escala de Discapacitat Expandida EDSS: Kurtzke	MSFC: Multiple Sclerosis Functional Composite
Camp	Neurologia	Neurologia
Família	Process / pipeline	Process / pipeline
Any d'origen	1983	1999
Autor original	John F. Kurtzke	Gary Cutter, Richard Rudick, and NMSS Consortium
Tipus	Clinician-rated	Clinician-administered performance test
Font seminal	Kurtzke, J. F. (1983). Rating neurologic impairment in multiple sclerosis: An expanded disability status scale (EDSS). Neurology, 33(11), 1444-1452.	Cutter, G. R., Baier, M. L., Rudick, R. A., et al. (1999). Development of a multiple sclerosis functional composite as a clinical trial outcome measure. Multiple Sclerosis, 5(4), 244-250.
Àlies	Expanded Disability Status Scale	MS Functional Composite
Relacionats	4	4
Resum	The EDSS is the most widely used clinical disability rating scale in multiple sclerosis research and practice. Developed by John Kurtzke in 1983, it provides a 0-10 ordinal scale capturing disease severity across eight neurological functional systems and functional status. The EDSS remains the primary endpoint in MS clinical trials and longitudinal cohort studies, with decades of prognostic and comparative data worldwide.	The Multiple Sclerosis Functional Composite (MSFC) is an objective, performance-based assessment of MS-related disability capturing three key functional domains: lower extremity mobility, upper extremity coordination, and cognitive/processing speed. Developed in 1999 by the National MS Society and adopted widely in clinical trials, the MSFC provides quantifiable endpoints complementing the Expanded Disability Status Scale (EDSS). The three-component design addresses EDSS limitations by including cognition and standardizing measurement via timed tasks.