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Cromatografia en columna×Planificació de rutes de síntesi×Cromatografia en capa fina×
CampQuímicaQuímicaQuímica
FamíliaProcess / pipelineProcess / pipelineProcess / pipeline
Any d'origen190319691956
Autor originalMikhail TsvetElias James CoreyEgon Stahl
TipusChromatographic separation techniqueStrategic planning methodologyChromatographic separation technique
Font seminalSkoog, D. A., Holler, F. J., & Crouch, S. R. (2017). Principles of Instrumental Analysis (7th ed.). Cengage Learning. ISBN: 978-1305577213Corey, E. J., & Cheng, X. M. (1991). The Logic of Chemical Synthesis. John Wiley & Sons. ISBN: 978-0471096092Sherma, J. (2003). Planar Chromatography. Analytical Chemistry, 75(12), 2783–2811. DOI ↗
Àliesliquid chromatography, column liquid chromatographyretrosynthesis, retrosynthetic analysis, synthetic route designTLC, planar chromatography
Relacionats333
ResumColumn chromatography is a liquid separation technique in which a stationary phase (typically silica gel or alumina) is packed into a vertical column, and a mobile phase (solvent) percolates through it to separate mixture components. Pioneered by Mikhail Tsvet in 1903, column chromatography remains the workhorse of organic chemistry laboratories for purifying reaction products and isolating target compounds.Synthesis route planning, grounded in retrosynthetic analysis, is a strategic approach to designing efficient chemical syntheses. Formalized by Elias James Corey in the 1960s (earning him the Nobel Prize in 1990), this methodology systematically deconstructs target molecules into simpler precursors and starting materials, enabling chemists to discover logical, economical, and practical synthesis routes.Thin-Layer Chromatography (TLC) is a planar chromatographic technique that separates compounds based on their differential affinities for a mobile and stationary phase. Developed by Egon Stahl in 1956, TLC remains one of the most accessible and widely used analytical methods in organic and inorganic chemistry, laboratories, and quality control.
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ScholarGateCompara mètodes: Column Chromatography · Synthesis Route Planning · Thin-Layer Chromatography. Recuperat el 2026-06-18 de https://scholargate.app/ca/compare