পদ্ধতির তুলনা করুন
নির্বাচিত পদ্ধতিগুলো পাশাপাশি পর্যালোচনা করুন; যে সারিগুলোয় পার্থক্য আছে সেগুলো চিহ্নিত করা হয়।
| মেটা-বিশ্লেষণমূলক র্যান্ডমাইজড ক্লিনিকাল ট্রায়াল× | ব্যক্তিগত রোগী তথ্য মেটা-বিশ্লেষণ× | |
|---|---|---|
| ক্ষেত্র≠ | মহামারীবিদ্যা | প্রমাণ সংশ্লেষণ |
| পরিবার | Process / pipeline | Process / pipeline |
| উদ্ভবের বছর≠ | 1976 (Glass coinage of meta-analysis); 1993 (Cochrane Collaboration formalization) | 1990s |
| প্রবর্তক≠ | Gene V. Glass (meta-analysis method); Cochrane Collaboration (systematic RCT pooling standards) | Cochrane Collaboration, Pioneered by Stewart & Clarke |
| ধরন≠ | Quantitative evidence-synthesis design | Method |
| মৌলিক উৎস≠ | Higgins, J. P. T., Thomas, J., Chandler, J., Cumpston, M., Li, T., Page, M. J., & Welch, V. A. (Eds.). (2019). Cochrane Handbook for Systematic Reviews of Interventions (2nd ed.). Wiley-Blackwell. ISBN: 978-1119536628 | Stewart, L. A., Clarke, M. J., & Cochrane IPD Meta-analysis Methods Group. (2015). Practical methodology of meta-analyses (including IPD) of randomised trials reporting time to event data. Cochrane Database of Systematic Reviews, 2015(10), MR000027. link ↗ |
| অপর নাম≠ | meta-analytic RCT, MA-RCT, meta-analysis of RCTs, pooled randomized trial analysis | IPD Meta-Analysis, Participant-Level Data Synthesis, One-Stage Meta-Analysis |
| সম্পর্কিত≠ | 3 | 1 |
| সারসংক্ষেপ≠ | A meta-analytic randomized clinical trial is a formal evidence-synthesis method that identifies, appraises, and statistically combines the results of multiple randomized clinical trials addressing the same clinical question. By pooling trial-level data, it produces a single, more precise estimate of treatment effect and quantifies between-trial heterogeneity, sitting at the apex of the evidence hierarchy for evaluating healthcare interventions. | Individual patient data meta-analysis (IPD-MA) is a systematic synthesis method where researchers obtain and analyze raw data at the patient level from multiple randomized controlled trials, rather than relying on published summary statistics (aggregate data). Pioneered by the Cochrane Collaboration and formalized by Stewart, Clarke, and Riley, IPD-MA is considered the gold standard for evidence synthesis because it enables consistent outcome definition across trials, robust subgroup analysis, and detection of treatment-covariate interactions. Though time-intensive and resource-demanding, IPD-MA provides the most reliable estimates of intervention effects and is preferred for critical clinical decisions, particularly for identifying which patients benefit most from treatment. |
| ScholarGateডেটাসেট ↗ |
|
|