قارن الطرق
راجع الطرق التي اخترتها جنبًا إلى جنب؛ الصفوف المختلفة مميَّزة.
| التحسين الطيفي للرامان السطحي (SERS)× | مطيافية الأشعة تحت الحمراء ذات الانعكاس الكلي الموهن (ATR-FTIR)× | رنين البلازمون السطحي× | |
|---|---|---|---|
| المجال | علم الطيف | علم الطيف | علم الطيف |
| العائلة | Process / pipeline | Process / pipeline | Process / pipeline |
| سنة النشأة≠ | 1974 | 1961 | 1971 |
| صاحب الطريقة≠ | Martin Fleischmann | Joop Fahrenfort | Erich Kretschmann |
| النوع≠ | Vibrational spectroscopy technique | Vibrational spectroscopy technique | Optical technique |
| المصدر التأسيسي≠ | Fleischmann, M., Hendra, P. J., & McQuillan, A. J. (1974). Raman spectra of pyridine adsorbed at a silver electrode. Chemical Physics Letters, 26(2), 163-166. DOI ↗ | Harrick, N. J. (1960). Study of physics of internal reflection from metals. Journal of Physics and Chemistry of Solids, 13(2), 143-155. link ↗ | Kretschmann, E. (1971). Determination of optical constants of metals by excitation of surface plasmons. Zeitschrift für Physik, 241(4), 313-324. link ↗ |
| الأسماء البديلة≠ | Surface-enhanced Raman scattering, SERS spectroscopy | ATR-IR, attenuated total reflectance, FTIR spectroscopy | SPR, surface plasmon, SPR biosensing |
| ذات صلة | 3 | 3 | 3 |
| الملخص≠ | Surface-Enhanced Raman Spectroscopy (SERS) amplifies weak Raman signals by many orders of magnitude when analyte molecules are adsorbed on specially prepared metal (typically silver or gold) nanostructured surfaces. Discovered by Fleischmann, Hendra, and McQuillan in 1974, SERS enables detection of vibrational signatures of single molecules and ultra-trace contaminants, revolutionizing analytical chemistry and forensics. | Attenuated Total Reflectance (ATR) Fourier Transform Infrared (FTIR) spectroscopy is a variant of conventional FTIR that measures infrared absorption through evanescent-wave interrogation of samples in direct contact with a high-refractive-index crystal. Developed by Harrick and Fahrenfort in the 1960s, ATR-FTIR is now the dominant form of FTIR spectroscopy, enabling rapid, non-destructive characterization of organic compounds, polymers, coatings, and biological materials without extensive sample preparation. | Surface Plasmon Resonance (SPR) is a real-time, label-free technique for detecting and monitoring biomolecular interactions at a sensor surface by measuring changes in the refractive index caused by ligand binding. Developed by Kretschmann in 1971 and applied to biosensing by Liedberg, Nylander, and Lundström in 1983, SPR is now a gold standard for measuring binding kinetics (association and dissociation rates) and equilibrium binding constants in protein interactions, antibody-antigen recognition, and drug discovery. |
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