方法证据记录
Schild Analysis
Schild analysis is a quantitative method for characterizing competitive receptor antagonism developed by Henry Schild in 1947. It uses dose-response curves in the presence and absence of antagonist to estimate the antagonist affinity constant (pA2), enabling standardized comparison of antagonist potency across drugs and experimental systems.
源记录
引文逐字复制自方法源记录。这些引文不代表任何层级的验证。
Schild Analysis of Receptor Antagonism
分类方法记录 · process-pipeline / pharmacology
- Schild, H. O. (1947). pA, a new scale for the measurement of drug antagonism. Journal of Physiology, 106(3), 337-357. · DOI 10.1111/j.1476-5381.1947.tb00336.x
- Arunlakshana, O., & Schild, H. O. (1959). Some quantitative uses of drug antagonisms. British Journal of Pharmacology and Chemotherapy, 14(1), 48-58. · DOI 10.1111/j.1476-5381.1959.tb00928.x
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