方法证据记录
Multi-omics Phylogenetic Analysis
Multi-omics phylogenetic analysis reconstructs evolutionary relationships among organisms by integrating sequence data from multiple molecular layers — genomes, transcriptomes, and proteomes — rather than relying on a single marker gene. By combining thousands of orthologous loci across omics layers, the approach dramatically reduces stochastic error, resolves ancient divergences that single-gene trees cannot, and yields a far more robust and well-supported topology of the tree of life or a focal clade.
源记录
引文逐字复制自方法源记录。这些引文不代表任何层级的验证。
Multi-omics Phylogenetic Analysis
分类方法记录 · process-pipeline / bioinformatics
- Delsuc, F., Brinkmann, H., & Philippe, H. (2005). Phylogenomics and the reconstruction of the tree of life. Nature Reviews Genetics, 6(5), 361–375. · DOI 10.1038/nrg1603
- Philippe, H., Brinkmann, H., Lavrov, D. V., Littlewood, D. T. J., Manuel, M., Wörheide, G., & Baurain, D. (2011). Resolving difficult phylogenetic questions: Why more sequences are not enough. PLoS Biology, 9(3), e1000602. · DOI 10.1371/journal.pbio.1000602
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