方法证据记录
Chou-Talalay Method
The Chou-Talalay method is a quantitative framework for analyzing drug interactions, developed by Ting-Chao Chou and Paul Talalay in 1983. It combines median-effect principle with the combination index (CI) to provide rigorous, model-independent assessment of synergistic, additive, or antagonistic drug effects.
源记录
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Chou-Talalay Combination Index Method
分类方法记录 · process-pipeline / pharmacology
- Chou, T. C., & Talalay, P. (1983). Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors. Advances in Enzyme Regulation, 22, 27-55. · DOI 10.1016/0065-2571(84)90007-4
- Chou, T. C. (1986). Quantitative analysis of the dose-effect relationship. Life Sciences, 38(26), 2347-2358. · URL
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