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Chỉ số Tổn thương Viêm mạch (VDI)×Chỉ số Hoạt động Bệnh Viêm Cột Sống Dính Khớp (BASDAI)×Chỉ số Hoạt động Bệnh Lupus Ban đỏ Hệ thống 2000 (SLEDAI-2K)×
Lĩnh vựcThấp khớp họcThấp khớp họcThấp khớp học
HọProcess / pipelineProcess / pipelineProcess / pipeline
Năm ra đời200319942002
Người khởi xướngExley et al.Garrett et al.Gladman et al.
LoạiClinician-ratedPatient-reported outcome (PRO)Clinician-rated
Công trình gốcExley AR, Bacon PA, Luqmani RA, Kitas GD, Gordon C, Pusey CD, Savage CO. Development and initial validation of the Vasculitis Damage Index (VDI) for systemic vasculitis. Arthritis & Rheumatism. 2003;48(7):2146-2157. link ↗Garrett S, Jenkinson T, Kennedy LG, Whitelock H, Gaisford P, Calin A. A new approach to defining disease status in ankylosing spondylitis: the Bath Ankylosing Spondylitis Disease Activity Index. The Journal of Rheumatology. 1994;21(12):2286-2291. link ↗Gladman DD, Ibañez D, Urowitz MB. Systemic Lupus Erythematosus Disease Activity Index 2000. The Journal of Rheumatology. 2002;29(2):288-291. link ↗
Tên gọi khácVDI, Vasculitis Permanent Organ Damage ScoreBASDAI, BAS-DAISLEDAI, SLEDAI-2K, SLE Disease Activity Index
Liên quan443
Tóm tắtThe VDI is a clinician-assessed measure of permanent organ damage in patients with systemic vasculitis, including ANCA-associated vasculitis (AAV), polyarteritis nodosa, and other necrotising vasculitides. Introduced by Exley et al. (2003), VDI captures cumulative irreversible damage across organ systems, complementing disease activity measures (such as the Birmingham Vasculitis Activity Score). Systemic vasculitis is characterised by inflammation of blood vessel walls, leading to ischaemia and permanent tissue damage. VDI acknowledges that damage accrues over time and is largely irreversible, making it a prognostically important measure distinct from transient inflammatory activity.The BASDAI is a patient-reported outcome measure of disease activity in ankylosing spondylitis (AS), a chronic inflammatory arthropathy affecting the spine and axial skeleton. Introduced by Garrett et al. in 1994, BASDAI uses six simple patient self-report items focused on the cardinal symptoms of AS: fatigue, spinal pain, peripheral joint involvement, and morning stiffness. As a PRO measure, BASDAI is practical for routine monitoring, responsive to treatment, and strongly associated with clinical outcomes and spinal damage progression, making it a cornerstone outcome in AS management and clinical trials.The SLEDAI is a comprehensive clinician-assessed measure of systemic lupus erythematosus (SLE) disease activity, capturing manifestations across multiple organ systems (cutaneous, renal, neuropsychiatric, hematologic, and serological). Introduced by Bombardier et al. (1992) and refined as SLEDAI-2K by Gladman et al. (2002), SLEDAI uses weighted scoring of 24 clinical and laboratory features to quantify overall SLE activity. It is the most widely used outcome measure in SLE research and clinical trials, enabling standardised assessment of disease progression, flare prediction, and treatment response in this complex multisystem disease.
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ScholarGateSo sánh phương pháp: Vasculitis Damage Index · Bath Ankylosing Spondylitis Disease Activity Index · Systemic Lupus Erythematosus Disease Activity Index. Truy cập ngày 2026-06-19 từ https://scholargate.app/vi/compare