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| Thang điểm Đánh giá Thống nhất Bệnh Huntington (UHDRS)× | EDSS: Thang đo Tình trạng Khuyết tật Mở rộng của Kurtzke× | |
|---|---|---|
| Lĩnh vực | Thần kinh học | Thần kinh học |
| Họ | Process / pipeline | Process / pipeline |
| Năm ra đời≠ | 1996 | 1983 |
| Người khởi xướng≠ | Huntington Study Group | John F. Kurtzke |
| Loại≠ | Clinician-rated and performance-based | Clinician-rated |
| Công trình gốc≠ | Huntington Study Group (1996). Unified Huntington's Disease Rating Scale: Reliability and consistency. Movement Disorders, 11(2), 136-142. link ↗ | Kurtzke, J. F. (1983). Rating neurologic impairment in multiple sclerosis: An expanded disability status scale (EDSS). Neurology, 33(11), 1444-1452. DOI ↗ |
| Tên gọi khác≠ | UHDRS, Huntington's Rating Scale | Expanded Disability Status Scale |
| Liên quan | 4 | 4 |
| Tóm tắt≠ | The Unified Huntington's Disease Rating Scale (UHDRS) is the comprehensive, multidomain assessment instrument for Huntington's disease, a neurodegenerative disorder caused by expanded CAG trinucleotide repeats. Developed by the Huntington Study Group in 1996, the UHDRS measures motor, cognitive, functional, and psychiatric manifestations of disease. The UHDRS is the gold-standard outcome measure in Huntington's disease clinical trials and longitudinal natural history studies. | The EDSS is the most widely used clinical disability rating scale in multiple sclerosis research and practice. Developed by John Kurtzke in 1983, it provides a 0-10 ordinal scale capturing disease severity across eight neurological functional systems and functional status. The EDSS remains the primary endpoint in MS clinical trials and longitudinal cohort studies, with decades of prognostic and comparative data worldwide. |
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