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| Phân tích phát sinh loài theo chuỗi thời gian× | Phylogenetic Analysis× | |
|---|---|---|
| Lĩnh vực | Tin sinh học | Tin sinh học |
| Họ | Process / pipeline | Process / pipeline |
| Năm ra đời≠ | 2000s (molecular clock methods earlier; BEAST framework 2007) | 1960s-1981 (distance trees ~1967; ML framework formalised 1981) |
| Người khởi xướng≠ | Alexei J. Drummond, Andrew Rambaut, and colleagues | Joseph Felsenstein (maximum likelihood framework); Walter Fitch and Emanuel Margoliash (distance methods) |
| Loại≠ | Evolutionary bioinformatics pipeline | Computational inference method |
| Công trình gốc≠ | Drummond, A. J., & Rambaut, A. (2007). BEAST: Bayesian evolutionary analysis by sampling trees. BMC Evolutionary Biology, 7, 214. DOI ↗ | Felsenstein, J. (2004). Inferring Phylogenies. Sinauer Associates. ISBN: 978-0878931774 |
| Tên gọi khác | temporal phylogenetics, time-resolved phylogenetics, molecular clock phylogenetics, phylodynamics | molecular phylogenetics, phylogenetic inference, evolutionary tree reconstruction, phylogenomics |
| Liên quan≠ | 6 | 5 |
| Tóm tắt≠ | Time-series phylogenetic analysis reconstructs the evolutionary history of organisms or genetic variants using sequences sampled at known time points. By incorporating sampling dates directly into the model, it estimates divergence times, substitution rates, and ancestral relationships on an absolute timescale — making it essential for studying viral outbreaks, ancient DNA dynamics, and rapid microbial evolution. | Phylogenetic analysis reconstructs the evolutionary history of organisms, genes, or proteins by comparing molecular sequence data and estimating the branching tree that best explains observed similarities and differences. Rooted in the work of Felsenstein and colleagues from the 1960s onward, it is a cornerstone technique in evolutionary biology, microbiology, epidemiology, and comparative genomics, supporting tasks from tracing viral outbreak origins to classifying novel species. |
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