So sánh phương pháp

	Mô hình cấu trúc biên mạnh mẽ	Mô hình cấu trúc biên (MSM)
Lĩnh vực	Suy luận nhân quả	Suy luận nhân quả
Họ	Regression model	Regression model
Năm ra đời	2000–2004	2000
Người khởi xướng	Robins, Hernán & Brumback; robustness extensions by Scharfstein, Rotnitzky, Lunceford & Davidian	James M. Robins, Miguel A. Hernan, Babette Brumback
Loại	Causal inference / weighted regression	Causal model / semiparametric weighting
Công trình gốc	Robins, J. M., Hernán, M. A., & Brumback, B. (2000). Marginal structural models and causal inference in epidemiology. Epidemiology, 11(5), 550-560.	Robins, J. M., Hernan, M. A., & Brumback, B. (2000). Marginal structural models and causal inference in epidemiology. Epidemiology, 11(5), 550-560.
Tên gọi khác	robust MSM, doubly-robust MSM, sandwich-SE MSM, robust IPTW marginal structural model	MSM, MSM-IPTW, marginal structural Cox model, weighted structural model
Liên quan	6	5
Tóm tắt	Robust Marginal Structural Models (robust MSMs) extend the standard MSM framework — which uses inverse probability of treatment weighting to handle time-varying confounding — by pairing IPTW estimation with sandwich (robust) standard errors or doubly-robust estimators. This combination yields valid causal estimates and reliable inference even when the outcome regression model is mildly misspecified or weights are moderately variable.	A marginal structural model is a causal modeling framework designed to estimate the effect of a time-varying treatment in the presence of time-varying confounders that are themselves affected by prior treatment. By reweighting observations with inverse probability of treatment weights, MSMs create a pseudo-population in which confounding is eliminated, enabling unbiased estimation of causal treatment contrasts even when standard regression adjustments would fail.