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	Thiết kế Trung tâm Tổ hợp dựa trên Rủi ro	Phân tích Chế độ và Ảnh hưởng Thất bại (FMEA)
Lĩnh vực	Thiết kế thí nghiệm	Thiết kế thí nghiệm
Họ	Process / pipeline	Process / pipeline
Năm ra đời	1951 (CCD); risk-based integration emerged in applied engineering literature from the 1990s onward	1949 (military); widespread industrial adoption 1970s–1980s
Người khởi xướng	Foundational CCD: George E. P. Box & K. B. Wilson (1951); risk integration adapted from engineering risk analysis traditions	U.S. Military / NASA (formalized by MIL-P-1629, 1949)
Loại	Experimental design with integrated risk assessment	Proactive risk analysis technique
Công trình gốc	Box, G. E. P., & Wilson, K. B. (1951). On the experimental attainment of optimum conditions. Journal of the Royal Statistical Society: Series B, 13(1), 1–45.	Stamatis, D. H. (2003). Failure Mode and Effect Analysis: FMEA from Theory to Execution (2nd ed.). ASQ Quality Press. ISBN: 978-0873895989
Tên gọi khác	Risk-informed CCD, CCD with risk assessment, Uncertainty-aware central composite design, Risk-integrated RSM	FMEA, Failure Modes and Effects Analysis, FMECA, Failure Mode Effects and Criticality Analysis
Liên quan	5	6
Tóm tắt	Risk-based Central Composite Design (Risk-based CCD) integrates formal risk identification and uncertainty quantification into the classical CCD framework. By coupling the rotatable second-order experimental structure of CCD with probabilistic risk metrics, engineers and scientists can simultaneously optimize process responses and characterize the risk of unacceptable outcomes — making it particularly valuable in regulated industries such as pharmaceuticals, chemical engineering, and advanced manufacturing.	Failure Mode and Effects Analysis (FMEA) is a structured, proactive risk management technique used to identify potential failure modes in a system, process, or product design, evaluate their consequences, and prioritize corrective actions before failures occur. Originally developed for the U.S. military in 1949 and later adopted by NASA, automotive, and manufacturing industries, FMEA is now a cornerstone quality-engineering tool embedded in standards such as AIAG-VDA and ISO 9001-aligned processes.