So sánh phương pháp

	Chuỗi ca bệnh tiến cứu	Nghiên cứu đoàn hệ tiền cứu
Lĩnh vực	Dịch tễ học	Dịch tễ học
Họ	Process / pipeline	Process / pipeline
Năm ra đời	Late 19th century onward; formalized in modern clinical epidemiology by the 1970s–1980s	1950s (systematic application); conceptual roots earlier
Người khởi xướng	Evolved from clinical case reporting traditions in 19th–20th century medicine	Richard Doll and Austin Bradford Hill (landmark application, 1951-1954); cohort methodology formalised by modern epidemiology textbooks
Loại	Observational study design	Observational longitudinal study design
Công trình gốc	Meinert, C. L. (1996). Clinical Trials: Design, Conduct, and Analysis. Oxford University Press. ISBN: 978-0195035681	Rothman, K. J., Greenland, S., & Lash, T. L. (2008). Modern Epidemiology (3rd ed.). Lippincott Williams & Wilkins. ISBN: 978-0781755641
Tên gọi khác	prospective case series study, forward-looking case series, prospective uncontrolled study, prospective observational case series	longitudinal cohort study, prospective follow-up study, incidence study, prospective observational cohort
Liên quan	5	6
Tóm tắt	A prospective case series is an observational study design in which a group of patients with a particular condition, exposure, or intervention is identified in advance and followed forward in time according to a pre-specified protocol. Data on outcomes, adverse events, and clinical course are collected as they occur, yielding higher data quality and temporal clarity than retrospective designs. No control group is included, so causal inference is limited, but the design is valuable for characterizing natural disease history, early safety signals, and feasibility of new interventions.	A prospective cohort study assembles a group of participants who are free of the outcome of interest at baseline, measures their exposures, and then follows them forward in time to record who develops the outcome. By collecting exposure data before outcomes occur, it establishes a clear temporal sequence that supports causal inference — a major advantage over retrospective designs. It is the cornerstone observational method in epidemiology and clinical research.