So sánh phương pháp

	Phân tích sống còn thực dụng	Thử nghiệm lâm sàng ngẫu nhiên thực dụng
Lĩnh vực	Dịch tễ học	Dịch tễ học
Họ	Process / pipeline	Process / pipeline
Năm ra đời	Conceptual framework: 1967; widespread application: 1990s–2000s	1967
Người khởi xướng	Schwartz & Lellouch (explanatory vs. pragmatic distinction, 1967); extended in survival analysis literature from the 1970s onward	Daniel Schwartz & Joseph Lellouch
Loại	Observational / experimental hybrid — time-to-event analysis in real-world or pragmatic-trial settings	Interventional study design
Công trình gốc	Ford, I., & Norrie, J. (2016). Pragmatic Trials. New England Journal of Medicine, 375(5), 454–463.	Schwartz, D., & Lellouch, J. (1967). Explanatory and pragmatic attitudes in therapeutical trials. Journal of Chronic Diseases, 20(8), 637–648.
Tên gọi khác	real-world survival analysis, pragmatic time-to-event analysis, effectiveness survival analysis, PSA	pragmatic RCT, effectiveness trial, real-world RCT, practical clinical trial
Liên quan	5	6
Tóm tắt	Pragmatic survival analysis applies time-to-event statistical methods within pragmatic or real-world settings, estimating how long patients survive, remain event-free, or retain treatment benefit under conditions of routine clinical practice. Unlike explanatory survival analyses conducted under tightly controlled trial conditions, the pragmatic variant embraces the heterogeneity, treatment switching, non-adherence, and competing events that characterise real-world patient populations, prioritising external validity over internal precision.	A pragmatic randomized clinical trial (pragmatic RCT) is an interventional study that tests whether a treatment works under routine clinical conditions, as opposed to the tightly controlled setting of an explanatory trial. It prioritizes broad eligibility, flexible delivery, and patient-relevant outcomes to answer the question 'Does this treatment work in everyday practice?' rather than 'Can this treatment work under ideal circumstances?' The distinction between pragmatic and explanatory trials was formally articulated by Schwartz and Lellouch in 1967 and operationalized by the PRECIS tool in 2009.