So sánh phương pháp

	Thí nghiệm Yếu tố Toàn diện Thực dụng	Thí nghiệm Phân thừa số
Lĩnh vực	Thiết kế thí nghiệm	Thiết kế thí nghiệm
Họ	Process / pipeline	Process / pipeline
Năm ra đời	1920s (factorial); 1967/2009 (pragmatic framework)	1945 (Finney); broader development 1950s–1970s by Box, Hunter
Người khởi xướng	Full factorial: R.A. Fisher (1920s); Pragmatic framing: Schwartz & Lellouch (1967), formalized by Thorpe et al. (2009)	D. J. Finney (formal development); foundations in Ronald Fisher's factorial design work
Loại	Experimental design	Quantitative experimental design
Công trình gốc	Thorpe, K. E., Zwarenstein, M., Oxman, A. D., Treweek, S., Furberg, C. D., Altman, D. G., ... & Chalmers, I. (2009). A pragmatic-explanatory continuum indicator summary (PRECIS): a tool to help trial designers. Journal of Clinical Epidemiology, 62(5), 464-475.	Box, G. E. P., Hunter, J. S., & Hunter, W. G. (2005). Statistics for Experimenters: Design, Innovation, and Discovery (2nd ed.). Wiley-Interscience. ISBN: 978-0471718130
Tên gọi khác	pragmatic factorial trial, real-world full factorial design, effectiveness full factorial experiment, pragmatic 2^k experiment	fractional factorial design, FFD, 2^(k-p) design, fractional replication
Liên quan	6	4
Tóm tắt	A pragmatic full factorial experiment combines the complete crossing of all factor levels (the full factorial structure) with the broad eligibility criteria, flexible delivery, and real-world conditions of a pragmatic trial. Every possible combination of factors is tested simultaneously, yielding both main effects and all interaction effects, while deliberately relaxing strict laboratory controls to reflect how interventions actually operate in practice.	A fractional factorial experiment is a resource-efficient experimental design that tests only a carefully chosen fraction of all possible factor-level combinations. By exploiting the principle that high-order interactions are usually negligible, it identifies the main effects and low-order interactions of k factors using far fewer runs than a full factorial design — making it the workhorse of industrial and engineering screening experiments.