So sánh phương pháp

	NODDI	Hình ảnh khuếch tán Kurtosis	Tỷ lệ Chuyển hóa Từ hóa	Thống kê Không gian Dựa trên Đường dẫn
Lĩnh vực	Chẩn đoán hình ảnh thần kinh	Chẩn đoán hình ảnh thần kinh	Chẩn đoán hình ảnh thần kinh	Chẩn đoán hình ảnh thần kinh
Họ	Process / pipeline	Process / pipeline	Process / pipeline	Process / pipeline
Năm ra đời	2012	2005	1989	2006
Người khởi xướng	Hui Zhang	Jens Jensen	Stephen Wolff	Stephen M. Smith
Loại	Microstructural white matter mapping	Microstructural white matter analysis	Tissue microstructure characterization	Diffusion MRI white matter analysis pipeline
Công trình gốc	Zhang, H., Schneider, T., Wheeler-Kingshott, C. A., & Alexander, D. C. (2012). NODDI: practical in vivo neurite orientation dispersion and density imaging of the human brain. NeuroImage, 61(4), 1000–1016.	Jensen, J. H., Helpern, J. A., Ramani, A., et al. (2005). Diffusional kurtosis imaging: the quantification of non-Gaussian water diffusion by magnetic resonance imaging. Magnetic Resonance in Medicine, 53(6), 1432–1440.	Wolff, S. D., & Balaban, R. S. (1989). Magnetization transfer contrast (MTC) and tissue water proton relaxation in vivo. Journal of Magnetic Resonance Imaging, 10(2), 135–148.	Smith, S. M., Jenkinson, M., Johansen-Berg, H., et al. (2006). Tract-based spatial statistics: voxelwise analysis of multi-subject diffusion data. NeuroImage, 31(4), 1487–1505.
Tên gọi khác	NODDI, neurite density mapping	DKI, non-Gaussian diffusion, diffusion kurtosis	MTR, magnetization transfer, MT imaging	TBSS, white matter skeleton analysis
Liên quan	3	3	3	3
Tóm tắt	Neurite Orientation Dispersion and Density Imaging (NODDI) is a biophysical diffusion MRI model that quantifies microstructural properties of white matter: neurite density (axonal density), orientation dispersion (fiber coherence), and isotropic diffusion (free water or cerebrospinal fluid). Introduced by Zhang and colleagues in 2012, NODDI provides biologically interpretable metrics directly linking diffusion MRI signals to tissue microstructure.	Diffusion Kurtosis Imaging (DKI) is an advanced diffusion MRI technique that quantifies non-Gaussian diffusion of water molecules, providing detailed information about tissue microstructure beyond conventional diffusion tensor imaging. Introduced by Jensen and colleagues in 2005, DKI detects deviations from normal Gaussian diffusion, revealing information about cellular compartmentalization and fiber heterogeneity.	Magnetisation Transfer Ratio (MTR) is an MRI method that measures the exchange of magnetization between free water protons and protons bound to macromolecules (primarily myelin lipids and proteins). Introduced by Wolff and Balaban in 1989, MTR reflects tissue macromolecular content and is particularly sensitive to myelination, providing a non-invasive estimate of myelin density.	Tract-Based Spatial Statistics (TBSS) is a voxel-wise analysis method for detecting group differences in white matter microstructure from diffusion MRI data. Published by Stephen M. Smith and colleagues in 2006, TBSS addresses registration and multiple comparison problems inherent in voxel-wise analysis by projecting individual FA maps onto a white matter skeleton derived from a population template.